Identification of CD25 as STAT5-Dependent Growth-Regulator of Leukemic Stem Cells in Ph+ CML

PURPOSE: In chronic myeloid leukemia (CML), leukemic stem cells (LSCs) represent a critical target of therapy. However, little is known about markers and targets expressed by LSCs. The aim of this project was to identify novel interesting markers of CML LSCs. EXPERIMENTAL DESIGN: CML LSCs were exami...

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Publicado no:Clin Cancer Res
Main Authors: Sadovnik, Irina, Hoelbl-Kovacic, Andrea, Herrmann, Harald, Eisenwort, Gregor, Cerny-Reiterer, Sabine, Warsch, Wolfgang, Hoermann, Gregor, Greiner, Georg, Blatt, Katharina, Peter, Barbara, Stefanzl, Gabriele, Berger, Daniela, Bilban, Martin, Herndlhofer, Susanne, Sill, Heinz, Sperr, Wolfgang R., Streubel, Berthold, Mannhalter, Christine, Holyoake, Tessa L., Sexl, Veronika, Valent, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817228/
https://ncbi.nlm.nih.gov/pubmed/26607600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0767
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