Expression of CD25 on leukemic stem cells in BCR-ABL1(+) CML: Potential diagnostic value and functional implications

Chronic myeloid leukemia (CML) is a stem cell–derived leukemia in which neoplastic cells exhibit the Philadelphia chromosome and the related oncoprotein BCR-ABL1. The disease is characterized by an accumulation of myeloid precursor cells in the peripheral blood and bone marrow (BM). A small fraction...

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Pubblicato in:Exp Hematol
Autori principali: Sadovnik, Irina, Herrmann, Harald, Eisenwort, Gregor, Blatt, Katharina, Hoermann, Gregor, Mueller, Niklas, Sperr, Wolfgang R., Valent, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044418/
https://ncbi.nlm.nih.gov/pubmed/28457753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.04.003
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