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Serum-tryptase at diagnosis: a novel biomarker improving prognostication in Ph(+) CML

Basophilia is an established prognostic variable in Ph-chromosome+ chronic myeloid leukemia (CML). However, in CML, basophils are often immature and thus escape microscopic quantification. We have previously shown that tryptase is produced and secreted by immature CML basophils. In the current study...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Sperr, Wolfgang R, Pfeiffer, Thomas, Hoermann, Gregor, Herndlhofer, Susanne, Sillaber, Christian, Mannhalter, Christine, Kundi, Michael, Valent, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300686/
https://ncbi.nlm.nih.gov/pubmed/25628944
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