Serum-tryptase at diagnosis: a novel biomarker improving prognostication in Ph(+) CML

Basophilia is an established prognostic variable in Ph-chromosome+ chronic myeloid leukemia (CML). However, in CML, basophils are often immature and thus escape microscopic quantification. We have previously shown that tryptase is produced and secreted by immature CML basophils. In the current study...

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Pubblicato in:Am J Cancer Res
Autori principali: Sperr, Wolfgang R, Pfeiffer, Thomas, Hoermann, Gregor, Herndlhofer, Susanne, Sillaber, Christian, Mannhalter, Christine, Kundi, Michael, Valent, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300686/
https://ncbi.nlm.nih.gov/pubmed/25628944
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