Serum-tryptase at diagnosis: a novel biomarker improving prognostication in Ph(+) CML

Basophilia is an established prognostic variable in Ph-chromosome+ chronic myeloid leukemia (CML). However, in CML, basophils are often immature and thus escape microscopic quantification. We have previously shown that tryptase is produced and secreted by immature CML basophils. In the current study...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Sperr, Wolfgang R, Pfeiffer, Thomas, Hoermann, Gregor, Herndlhofer, Susanne, Sillaber, Christian, Mannhalter, Christine, Kundi, Michael, Valent, Peter
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300686/
https://ncbi.nlm.nih.gov/pubmed/25628944
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