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Overexpression of IL-3Rα on CD34(+)CD38(−) stem cells defines leukemia-initiating cells in Fanconi anemia AML
Patients with Fanconi anemia (FA) have a high risk of developing acute myeloid leukemia (AML). In this study, we attempted to identify cell-surface markers for leukemia-initiating cells in FA-AML patients. We found that the IL-3 receptor-α (IL-3Rα) is a promising candidate as an leukemia-initiating...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087476/ https://ncbi.nlm.nih.gov/pubmed/21330473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-309179 |
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