TLR8-dependent TNF-α overexpression in Fanconi anemia group C cells

Tumor necrosis factor alpha (TNF-α) production is abnormally high in Fanconi anemia (FA) cells and contributes to the hematopoietic defects seen in FA complementation group C–deficient (Fancc(−/−)) mice. Applying gene expression microarray and proteomic methods to studies on FANCC-deficient cells we...

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Detalhes bibliográficos
Main Authors: Vanderwerf, Scott M., Svahn, Johanna, Olson, Susan, Rathbun, R. Keaney, Harrington, Christina, Yates, Jane, Keeble, Winifred, Anderson, David C., Anur, Praveen, Pereira, Noemi F., Pilonetto, Daniela V., Pasquini, Ricardo, Bagby, Grover C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796134/
https://ncbi.nlm.nih.gov/pubmed/19850743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-222414
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