A clinically relevant population of leukemic CD34(+)CD38(−) cells in acute myeloid leukemia

Relapse of acute myeloid leukemia (AML) is thought to reflect the failure of current therapies to adequately target leukemia stem cells (LSCs), the rare, resistant cells presumed responsible for maintenance of the leukemia and typically enriched in the CD34(+)CD38(−) cell population. Despite the con...

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Hlavní autoři: Gerber, Jonathan M., Smith, B. Douglas, Ngwang, Brownhilda, Zhang, Hao, Vala, Milada S., Morsberger, Laura, Galkin, Steven, Collector, Michael I., Perkins, Brandy, Levis, Mark J., Griffin, Constance A., Sharkis, Saul J., Borowitz, Michael J., Karp, Judith E., Jones, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Myeloid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325044/
https://ncbi.nlm.nih.gov/pubmed/22262762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-364182
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