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Immunoprofiling of leukemic stem cells CD34+/CD38−/CD123+ delineate FLT3/ITD-positive clones

Abstract Background Acute myeloid leukemia (AML) is a heterogeneous clonal disorder presenting with accumulation of proliferating undifferentiated blasts. Xenograft transplantation studies have demonstrated a rare population of leukemia-initiating cells called leukemic stem cells (LSCs) capable of p...

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Detalhes bibliográficos
Main Authors: Adhra Al-Mawali, David Gillis, Ian Lewis
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2016-07-01
Colecção:Journal of Hematology & Oncology
Assuntos:
Acesso em linha:http://link.springer.com/article/10.1186/s13045-016-0292-z
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