Characteristics and Prognosis of Adult Acute Myeloid Leukemia with Internal Tandem Duplication in the FLT3 Gene

Objectives: Constitutive activation of the fms-like tyrosine kinase 3 (FLT3) receptor by internal tandem duplication (ITD) of the juxtamembrane region has been described in patients with acute myeloid leukemia. FLT3/ITDs are present in about 20-30% of all acute myeloid leukemia cases. It has been sh...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Adhra Al-Mawali, David Gillis, Ian Lewis
Formato: Artigo
Idioma:Inglês
Publicado em: Oman Medical Specialty Board 2013-11-01
Colecção:Oman Medical Journal
Assuntos:
Acute Myeloid Leukemia
M1
FLT3 gene
Tandem duplication
Prognosis.
Acesso em linha:http://www.omjournal.org/fultext_PDF.aspx?DetailsID=449&type=fultext
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados