A clinically relevant population of leukemic CD34(+)CD38(−) cells in acute myeloid leukemia

Relapse of acute myeloid leukemia (AML) is thought to reflect the failure of current therapies to adequately target leukemia stem cells (LSCs), the rare, resistant cells presumed responsible for maintenance of the leukemia and typically enriched in the CD34(+)CD38(−) cell population. Despite the con...

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Bibliographic Details
Main Authors: Gerber, Jonathan M., Smith, B. Douglas, Ngwang, Brownhilda, Zhang, Hao, Vala, Milada S., Morsberger, Laura, Galkin, Steven, Collector, Michael I., Perkins, Brandy, Levis, Mark J., Griffin, Constance A., Sharkis, Saul J., Borowitz, Michael J., Karp, Judith E., Jones, Richard J.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2012
Subjects:
Myeloid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325044/
https://ncbi.nlm.nih.gov/pubmed/22262762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-364182
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