A clinically relevant population of leukemic CD34(+)CD38(−) cells in acute myeloid leukemia

Relapse of acute myeloid leukemia (AML) is thought to reflect the failure of current therapies to adequately target leukemia stem cells (LSCs), the rare, resistant cells presumed responsible for maintenance of the leukemia and typically enriched in the CD34(+)CD38(−) cell population. Despite the con...

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Main Authors: Gerber, Jonathan M., Smith, B. Douglas, Ngwang, Brownhilda, Zhang, Hao, Vala, Milada S., Morsberger, Laura, Galkin, Steven, Collector, Michael I., Perkins, Brandy, Levis, Mark J., Griffin, Constance A., Sharkis, Saul J., Borowitz, Michael J., Karp, Judith E., Jones, Richard J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2012
Ábhair:
Myeloid Neoplasia
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325044/
https://ncbi.nlm.nih.gov/pubmed/22262762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-364182
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