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Synthesis and Anticancer Activity of Glucosylated Podophyllotoxin Derivatives Linked via 4β-Triazole Rings

A series of 4β-triazole-linked glucose podophyllotoxin conjugates have been designed and synthesized by employing a click chemistry approach. All the compounds were evaluated for their anticancer activity against a panel of five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, SW480) using M...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zi, Cheng-Ting, Xu, Feng-Qing, Li, Gen-Tao, Li, Yan, Ding, Zhong-Tao, Zhou, Jun, Jiang, Zi-Hua, Hu, Jiang-Miao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270044/
https://ncbi.nlm.nih.gov/pubmed/24232736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181113992
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