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Synthesis and Evaluation of New Podophyllotoxin Derivatives with in Vitro Anticancer Activity
A series of novel podophyllotoxin derivatives were designed and synthesized. The cytotoxic activities of these compounds were tested against three tumor cell lines (HeLa, K562, and K562/A02). Most of the derivatives (IC(50) = 1–20 μM) were found to have stronger cell growth inhibitory activity than...
Gorde:
| Argitaratua izan da: | Molecules |
|---|---|
| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
MDPI
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6332074/ https://ncbi.nlm.nih.gov/pubmed/26154885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200712266 |
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