Cargando...

Synthesis and Evaluation of New Podophyllotoxin Derivatives with in Vitro Anticancer Activity

A series of novel podophyllotoxin derivatives were designed and synthesized. The cytotoxic activities of these compounds were tested against three tumor cell lines (HeLa, K562, and K562/A02). Most of the derivatives (IC(50) = 1–20 μM) were found to have stronger cell growth inhibitory activity than...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Cheng, Wei-Hua, Shang, Hai, Niu, Cong, Zhang, Zhong-Heng, Zhang, Li-Ming, Chen, Hong, Zou, Zhong-Mei
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332074/
https://ncbi.nlm.nih.gov/pubmed/26154885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200712266
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!