Yüklüyor......
Excitotoxic superoxide production and neuronal death require both ionotropic and non-ionotropic NMDA receptor signaling
NMDA-type glutamate receptors (NMDAR) trigger superoxide production by neuronal NADPH oxidase-2 (NOX2), which if sustained leads to cell death. This process involves Ca(2+) influx through NMDAR channels. By contrast, comparable Ca(2+) influx by other routes does not induce NOX2 activation or cell de...
Kaydedildi:
| Yayımlandı: | Sci Rep |
|---|---|
| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2018
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6269523/ https://ncbi.nlm.nih.gov/pubmed/30504838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35725-5 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|