Whole genome duplication is an early event leading to aneuploidy in IDH-wild type glioblastoma

Glioblastoma, the most frequent and lethal form of glioma, displays chromosome instability and recurrent somatic copy number alterations (SCNA). Chromothripsis and whole genome duplication (WGD) have been recently identified in cancer. In the present study, we analyzed SCNA and determine the ploidy...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Boisselier, Blandine, Dugay, Frédéric, Belaud-Rotureau, Marc-Antoine, Coutolleau, Anne, Garcion, Emmanuel, Menei, Philippe, Guardiola, Philippe, Rousseau, Audrey
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267593/
https://ncbi.nlm.nih.gov/pubmed/30542515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26330
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