Whole genome duplication is an early event leading to aneuploidy in IDH-wild type glioblastoma

Glioblastoma, the most frequent and lethal form of glioma, displays chromosome instability and recurrent somatic copy number alterations (SCNA). Chromothripsis and whole genome duplication (WGD) have been recently identified in cancer. In the present study, we analyzed SCNA and determine the ploidy...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Boisselier, Blandine, Dugay, Frédéric, Belaud-Rotureau, Marc-Antoine, Coutolleau, Anne, Garcion, Emmanuel, Menei, Philippe, Guardiola, Philippe, Rousseau, Audrey
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267593/
https://ncbi.nlm.nih.gov/pubmed/30542515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26330
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