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Thy-1 (CD90) Signaling Preferentially Promotes RORγt Expression and a Th17 Response

Thy-1 (CD90) is a glycosylphosphatidylinositol-anchored protein (GPI-AP) with signaling properties that is abundant on mouse T cells. Upon antibody-mediated crosslinking, Thy-1 provides a T cell receptor (TcR)-like signal that is sufficient to drive CD4(+) T cell proliferation and differentiation in...

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書目詳細資料
發表在:Front Cell Dev Biol
Main Authors: Furlong, Suzanne, Coombs, Melanie R. Power, Ghassemi-Rad, Javad, Hoskin, David W.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265317/
https://ncbi.nlm.nih.gov/pubmed/30533413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00158
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