TH17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ

The functional differentiation of T cells is mediated by lineage-specific transcription factors. TH17 has been recently identified as a distinct TH lineage that mediates tissue inflammation. RORγ was previously shown to regulate TH17 differentiation; RORγ deficiency, however, did not completely abol...

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Detalhes bibliográficos
Main Authors: Yang, Xuexian O., Pappu, Bhanu, Nurieva, Roza, Akimzhanov, Askar, Kang, Hong Soon, Chung, Yeonseok, Ma, Li, Shah, Bhavin, Panopoulos, Athanasia D., Schluns, Kimberly, Watowich, Stephanie S., Tian, Qiang, Jetten, Anton M., Dong, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587175/
https://ncbi.nlm.nih.gov/pubmed/18164222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.11.016
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