TH17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ

The functional differentiation of T cells is mediated by lineage-specific transcription factors. TH17 has been recently identified as a distinct TH lineage that mediates tissue inflammation. RORγ was previously shown to regulate TH17 differentiation; RORγ deficiency, however, did not completely abol...

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Hoofdauteurs: Yang, Xuexian O., Pappu, Bhanu, Nurieva, Roza, Akimzhanov, Askar, Kang, Hong Soon, Chung, Yeonseok, Ma, Li, Shah, Bhavin, Panopoulos, Athanasia D., Schluns, Kimberly, Watowich, Stephanie S., Tian, Qiang, Jetten, Anton M., Dong, Chen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587175/
https://ncbi.nlm.nih.gov/pubmed/18164222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.11.016
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