Retinoid acid-related orphan receptor γ, RORγ, participates in diurnal transcriptional regulation of lipid metabolic genes

The hepatic circadian clock plays a pivotal role in regulating major aspects of energy homeostasis and lipid metabolism. In this study, we show that RORγ robustly regulates the rhythmic expression of several lipid metabolic genes, including the insulin-induced gene 2a, Insig2a, elongation of very lo...

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Hlavní autoři: Takeda, Yukimasa, Kang, Hong Soon, Lih, Fred B., Jiang, Hongfeng, Blaner, William S., Jetten, Anton M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176349/
https://ncbi.nlm.nih.gov/pubmed/25143535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku766
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