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Analysis of the Transcriptional Activity of Retinoic Acid-related Orphan Receptors (RORs) and Inhibition by Inverse Agonists

Here, we describe several assays to analyze the transcriptional activity of retinoic acid-related orphan receptors (RORs) and the effect of inverse agonists on their activity. One assay measures the effect of an inverse agonist on the transcriptional activation of a luciferase reporter by RORs in a...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Takeda, Yukimasa, Kang, Hong Soon, Jetten, Anton M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785025/
https://ncbi.nlm.nih.gov/pubmed/31041748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9195-2_15
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