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Retinoic Acid-Related Orphan Receptor γ (RORγ): A Novel Participant in the Diurnal Regulation of Hepatic Gluconeogenesis and Insulin Sensitivity

The hepatic circadian clock plays a key role in the daily regulation of glucose metabolism, but the precise molecular mechanisms that coordinate these two biological processes are not fully understood. In this study, we identify a novel connection between the regulation of RORγ by the clock machiner...

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Autors principals: Takeda, Yukimasa, Kang, Hong Soon, Freudenberg, Johannes, DeGraff, Laura M., Jothi, Raja, Jetten, Anton M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022472/
https://ncbi.nlm.nih.gov/pubmed/24831725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004331
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