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RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo
In this study, we demonstrate that the lack of retinoic acid-related orphan receptor (ROR) γ or α expression in mice significantly reduced the peak expression level of Cry1, Bmal1, E4bp4, Rev-Erbα and Per2 in an ROR isotype- and tissue-selective manner without affecting the phase of their rhythmic e...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458568/ https://ncbi.nlm.nih.gov/pubmed/22753030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks630 |
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