Retinoid-related orphan receptor γ (RORγ) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis

To identify the physiological functions of the retinoid-related orphan receptor γ (RORγ), a member of the nuclear receptor superfamily, mice deficient in RORγ function were generated by targeted disruption. RORγ(−/−) mice lack peripheral and mesenteric lymph nodes and Peyer's patches, indicatin...

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Библиографические подробности
Главные авторы: Kurebayashi, Shogo, Ueda, Eiichiro, Sakaue, Morito, Patel, Dhavalkumar D., Medvedev, Alex, Zhang, Feng, Jetten, Anton M.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2000
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC27750/
https://ncbi.nlm.nih.gov/pubmed/10963675
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