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TH17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ
The functional differentiation of T cells is mediated by lineage-specific transcription factors. TH17 has been recently identified as a distinct TH lineage that mediates tissue inflammation. RORγ was previously shown to regulate TH17 differentiation; RORγ deficiency, however, did not completely abol...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587175/ https://ncbi.nlm.nih.gov/pubmed/18164222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.11.016 |
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