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Therapeutic potential of carbonyl-scavenging carnosine derivative in metabolic disorders
Obesity and overnutrition increase levels of reactive sugar- and lipid-derived aldehydes called reactive carbonyl species (RCS). Increased tissue and circulating RCS levels have been tied to insulin resistance and inflammation, but previous pharmacological approaches to target RCS have had equivocal...
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| Gepubliceerd in: | J Clin Invest |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6264722/ https://ncbi.nlm.nih.gov/pubmed/30352430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124304 |
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