A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress

Sugar- and lipid-derived aldehydes are reactive carbonyl species (RCS) frequently used as surrogate markers of oxidative stress in obesity. A pathogenic role for RCS in metabolic diseases of obesity remains controversial, however, partly because of their highly diffuse and broad reactivity and the l...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Anderson, Ethan J., Vistoli, Giulio, Katunga, Lalage A., Funai, Katsuhiko, Regazzoni, Luca, Monroe, T. Blake, Gilardoni, Ettore, Cannizzaro, Luca, Colzani, Mara, De Maddis, Danilo, Rossoni, Giuseppe, Canevotti, Renato, Gagliardi, Stefania, Carini, Marina, Aldini, Giancarlo
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264636/
https://ncbi.nlm.nih.gov/pubmed/30226473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94307
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