A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress

Sugar- and lipid-derived aldehydes are reactive carbonyl species (RCS) frequently used as surrogate markers of oxidative stress in obesity. A pathogenic role for RCS in metabolic diseases of obesity remains controversial, however, partly because of their highly diffuse and broad reactivity and the l...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Anderson, Ethan J., Vistoli, Giulio, Katunga, Lalage A., Funai, Katsuhiko, Regazzoni, Luca, Monroe, T. Blake, Gilardoni, Ettore, Cannizzaro, Luca, Colzani, Mara, De Maddis, Danilo, Rossoni, Giuseppe, Canevotti, Renato, Gagliardi, Stefania, Carini, Marina, Aldini, Giancarlo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264636/
https://ncbi.nlm.nih.gov/pubmed/30226473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94307
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