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Therapeutic potential of carbonyl-scavenging carnosine derivative in metabolic disorders

Obesity and overnutrition increase levels of reactive sugar- and lipid-derived aldehydes called reactive carbonyl species (RCS). Increased tissue and circulating RCS levels have been tied to insulin resistance and inflammation, but previous pharmacological approaches to target RCS have had equivocal...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Haus, Jacob M., Thyfault, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264722/
https://ncbi.nlm.nih.gov/pubmed/30352430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124304
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