Carnosine: can understanding its actions on energy metabolism and protein homeostasis inform its therapeutic potential?

The dipeptide carnosine (β-alanyl-L-histidine) has contrasting but beneficial effects on cellular activity. It delays cellular senescence and rejuvenates cultured senescent mammalian cells. However, it also inhibits the growth of cultured tumour cells. Based on studies in several organisms, we specu...

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Bibliografiske detaljer
Main Authors: Hipkiss, Alan R, Cartwright, Stephanie P, Bromley, Clare, Gross, Stephane R, Bill, Roslyn M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602167/
https://ncbi.nlm.nih.gov/pubmed/23442334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-7-38
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