Prion pathogenesis is unaltered in a mouse strain with a permeable blood-brain barrier

Transmissible spongiform encephalopathies (TSEs) are caused by the prion, which consists essentially of PrP(Sc), an aggregated, conformationally modified form of the cellular prion protein (PrP(C)). Although TSEs can be experimentally transmitted by intracerebral inoculation, most instances of infec...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Keller, Annika, Nuvolone, Mario, Abakumova, Irina, Chincisan, Andra, Reimann, Regina, Avar, Merve, Heinzer, Daniel, Hornemann, Simone, Wagner, Josephin, Kirschenbaum, Daniel, Voigt, Fabian F., Zhu, Caihong, Regli, Luca, Helmchen, Fritjof, Aguzzi, Adriano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264140/
https://ncbi.nlm.nih.gov/pubmed/30496289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007424
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