Prion pathogenesis is unaltered in a mouse strain with a permeable blood-brain barrier

Transmissible spongiform encephalopathies (TSEs) are caused by the prion, which consists essentially of PrP(Sc), an aggregated, conformationally modified form of the cellular prion protein (PrP(C)). Although TSEs can be experimentally transmitted by intracerebral inoculation, most instances of infec...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Keller, Annika, Nuvolone, Mario, Abakumova, Irina, Chincisan, Andra, Reimann, Regina, Avar, Merve, Heinzer, Daniel, Hornemann, Simone, Wagner, Josephin, Kirschenbaum, Daniel, Voigt, Fabian F., Zhu, Caihong, Regli, Luca, Helmchen, Fritjof, Aguzzi, Adriano
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264140/
https://ncbi.nlm.nih.gov/pubmed/30496289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007424
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires