Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy

In view of the multifactorial nature of Alzheimer’s disease (AD), multitarget small molecules (MTSM) represent the most potent and attractive therapeutic strategy to design new drugs for Alzheimer’s disease therapy. The new MTSM KojoTacrines (KTs) were designed and synthesized by juxtaposition of se...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Dgachi, Youssef, Martin, Hélène, Malek, Rim, Jun, Daniel, Janockova, Jana, Sepsova, Vendula, Soukup, Ondrej, Iriepa, Isabel, Moraleda, Ignacio, Maalej, Emna, Carreiras, M. Carmo, Refouvelet, Bernard, Chabchoub, Fakher, Marco-Contelles, José, Ismaili, Lhassane
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263107/
https://ncbi.nlm.nih.gov/pubmed/30482062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1538136
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