Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy

Alzheimer’s disease (AD) is multifactorial disease characterized by the accumulation of abnormal extracellular deposits of amyloid-beta (Aβ) peptide, and intracellular neurofibrillary tangles (NFTs), along with dramatic neuronal death and decreased levels of choline acetyltransferase. Given the limi...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zribi, Lazhar, Pachòn-Angona, Irene, Bautista-Aguilera, Òscar M., Diez-Iriepa, Daniel, Marco-Contelles, José, Ismaili, Lhassane, Iriepa, Isabel, Chabchoub, Fakher
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397274/
https://ncbi.nlm.nih.gov/pubmed/32668671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25143190
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