Intramembrane ionic protein–lipid interaction regulates integrin structure and function

Protein transmembrane domains (TMDs) are generally hydrophobic, but our bioinformatics analysis shows that many TMDs contain basic residues at terminal regions. Physiological functions of these membrane-snorkeling basic residues are largely unclear. Here, we show that a membrane-snorkeling Lys resid...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Guo, Jun, Zhang, Youhua, Li, Hua, Chu, Huiying, Wang, Qinshu, Jiang, Shutan, Li, Yan, Shen, Hongbin, Li, Guohui, Chen, Jianfeng, Xu, Chenqi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261646/
https://ncbi.nlm.nih.gov/pubmed/30427828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006525
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