Intramembrane ionic protein–lipid interaction regulates integrin structure and function

Protein transmembrane domains (TMDs) are generally hydrophobic, but our bioinformatics analysis shows that many TMDs contain basic residues at terminal regions. Physiological functions of these membrane-snorkeling basic residues are largely unclear. Here, we show that a membrane-snorkeling Lys resid...

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Dades bibliogràfiques
Publicat a:PLoS Biol
Autors principals: Guo, Jun, Zhang, Youhua, Li, Hua, Chu, Huiying, Wang, Qinshu, Jiang, Shutan, Li, Yan, Shen, Hongbin, Li, Guohui, Chen, Jianfeng, Xu, Chenqi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261646/
https://ncbi.nlm.nih.gov/pubmed/30427828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006525
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