Intramembrane ionic protein–lipid interaction regulates integrin structure and function

Protein transmembrane domains (TMDs) are generally hydrophobic, but our bioinformatics analysis shows that many TMDs contain basic residues at terminal regions. Physiological functions of these membrane-snorkeling basic residues are largely unclear. Here, we show that a membrane-snorkeling Lys resid...

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Vydáno v:PLoS Biol
Hlavní autoři: Guo, Jun, Zhang, Youhua, Li, Hua, Chu, Huiying, Wang, Qinshu, Jiang, Shutan, Li, Yan, Shen, Hongbin, Li, Guohui, Chen, Jianfeng, Xu, Chenqi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261646/
https://ncbi.nlm.nih.gov/pubmed/30427828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006525
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