Regulation of EGFR nanocluster formation by ionic protein-lipid interaction

The abnormal activation of epidermal growth factor receptor (EGFR) is strongly associated with a variety of human cancers but the underlying molecular mechanism is not fully understood. By using direct stochastic optical reconstruction microscopy (dSTORM), we find that EGFR proteins form nanocluster...

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Autors principals: Wang, Ye, Gao, Jing, Guo, Xingdong, Tong, Ti, Shi, Xiaoshan, Li, Lunyi, Qi, Miao, Wang, Yajie, Cai, Mingjun, Jiang, Junguang, Xu, Chenqi, Ji, Hongbin, Wang, Hongda
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123299/
https://ncbi.nlm.nih.gov/pubmed/25001389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.89
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