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Deregulation of CRAD-Controlled Cytoskeleton Initiates Mucinous Colorectal Cancer via β-Catenin
The epithelial integrity is maintained by the cytoskeleton and cell adhesion. However, it remains unknown how deregulated cytoskeleton is associated with cancer. We identified Cancer-related Regulator of Actin Dynamics (CRAD) as frequently mutated or transcriptionally downregulated in colorectal can...
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| Veröffentlicht in: | Nat Cell Biol |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6261439/ https://ncbi.nlm.nih.gov/pubmed/30361697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0215-z |
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