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Deregulation of CRAD-Controlled Cytoskeleton Initiates Mucinous Colorectal Cancer via β-Catenin

The epithelial integrity is maintained by the cytoskeleton and cell adhesion. However, it remains unknown how deregulated cytoskeleton is associated with cancer. We identified Cancer-related Regulator of Actin Dynamics (CRAD) as frequently mutated or transcriptionally downregulated in colorectal can...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Jung, Youn-Sang, Wang, Wenqi, Jun, Sohee, Zhang, Jie, Srivastava, Mrinal, Kim, Moon Jong, Lien, Esther M., Shang, Joan, Chen, Junjie, McCrea, Pierre D., Zhang, Songlin, Park, Jae-Il
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261439/
https://ncbi.nlm.nih.gov/pubmed/30361697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0215-z
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