Wird geladen...

Bystander or No Bystander for Gene Directed Enzyme Prodrug Therapy

Gene directed enzyme prodrug therapy (GDEPT) of cancer aims to improve the selectivity of chemotherapy by gene transfer, thus enabling target cells to convert non-toxic prodrugs to cytotoxic drugs. A zone of cell kill around gene-modified cells due to transfer of toxic metabolites, known as the byst...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Dachs, Gabi U., Hunt, Michelle A., Syddall, Sophie, Singleton, Dean C., Patterson, Adam V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255103/
https://ncbi.nlm.nih.gov/pubmed/19924084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14114517
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!