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Photodynamic therapy enhances the efficacy of gene-directed enzyme prodrug therapy
INTRODUCTION: Gene-directed enzyme prodrug therapy (GDEPT) employing the cytosine deaminase (CD) gene, which encodes an enzyme that converts the nontoxic agent 5-fluorocytosine (5-FC) into the chemotherapeutic drug 5-fluorouracil (5-FU), has shown promise both in experimental animals and in clinical...
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| Publicado no: | Photodiagnosis Photodyn Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474194/ https://ncbi.nlm.nih.gov/pubmed/28257943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pdpdt.2017.02.016 |
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