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Gene-Directed Enzyme Prodrug Therapy

As one targeting strategy of prodrug delivery, gene-directed enzyme prodrug therapy (GDEPT) promises to realize the targeting through its three key features in cancer therapy—cell-specific gene delivery and expression, controlled conversion of prodrugs to drugs in target cells, and expanded toxicity...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Zhang, Jin, Kale, Vijay, Chen, Mingnan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287286/
https://ncbi.nlm.nih.gov/pubmed/25338741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9675-7
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