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Enzyme/Prodrug Systems for Cancer Gene Therapy

The use of enzyme/prodrug system has gained attention because it could help improve the efficacy and safety of conventional cancer chemotherapies. In this approach, cancer cells are first transfected with a gene that can express an enzyme with ability to convert a non-toxic prodrug into its active c...

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Detalhes bibliográficos
Publicado no:Curr Pharmacol Rep
Main Authors: Malekshah, Obeid M., Chen, Xuguang, Nomani, Alireza, Sarkar, Siddik, Hatefi, Arash
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193473/
https://ncbi.nlm.nih.gov/pubmed/28042530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40495-016-0073-y
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