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Progress and Problems with the Use of Suicide Genes for Targeted Cancer Therapy

Among various gene therapy methods for cancer, suicide gene therapy attracts a special attention because it allows selective conversion of non-toxic compounds into cytotoxic drugs inside cancer cells. As a result, therapeutic index can be increased significantly by introducing high concentrations of...

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Detalhes bibliográficos
Publicado no:Adv Drug Deliv Rev
Main Authors: Karjoo, Zahra, Chen, Xuguang, Hatefi, Arash
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758904/
https://ncbi.nlm.nih.gov/pubmed/26004498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2015.05.009
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