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HSV-TK/GCV Cancer Suicide Gene Therapy by a Designed Recombinant Multifunctional Vector

The objective of this research was to evaluate the efficacy of a recombinant non-viral vector for targeted delivery of a thymidine kinase (TK) suicide gene to xenograft SKOV-3 tumors. The vector was genetically engineered and used to condense TK gene into particles of less than 100nm in size. The na...

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Detalhes bibliográficos
Main Authors: Wang, Yuhua, Canine, Brenda F., Hatefi, Arash
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024463/
https://ncbi.nlm.nih.gov/pubmed/20817124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2010.08.003
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