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Study on the effect of BMSCs-EGFP-tk as mediator of HSV1-tk/GCV suicide gene therapy directed against A549 in vitro

This study aims to observe the expression of HSV1-tk in mouse bone marrow mesenchymal stem cells (BMSCs-EGFP-tk) and detect the inhibition and killing effects of BMSCs as mediator of HSV1-tk/GCV on A549 cells in vitro, which can provide the experimental basis for gene therapy of lung cancer. We cons...

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Autori principali: Yang, Kun, Xu, Wen-Gui, Liu, Yong-Zhe, Meng, Xiang-Rui, Chen, Peng, Wu, Li-Chuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211835/
https://ncbi.nlm.nih.gov/pubmed/25356185
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