Bioengineered Adipose-Derived Stem Cells for Targeted Enzyme-Prodrug Therapy of Ovarian Cancer Intraperitoneal Metastasis

The objective of this study was to develop a stem cell-based system for targeted suicide gene therapy of recurrent, metastatic, and unresectable ovarian cancer. Malignant cells were obtained from the ascites of a patient with advanced recurrent epithelial ovarian cancer (named OVASC-1). Cancer cells...

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Bibliographic Details
Published in:J Control Release
Main Authors: Malekshah, Obeid M., Sarkar, Siddik, Nomani, Alireza, Patel, Niket, Javidian, Parisa, Goedken, Michael, Polunas, Marianne, Louro, Pedro, Hatefi, Arash
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884134/
https://ncbi.nlm.nih.gov/pubmed/31499084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.09.006
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