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Bystander or No Bystander for Gene Directed Enzyme Prodrug Therapy

Gene directed enzyme prodrug therapy (GDEPT) of cancer aims to improve the selectivity of chemotherapy by gene transfer, thus enabling target cells to convert non-toxic prodrugs to cytotoxic drugs. A zone of cell kill around gene-modified cells due to transfer of toxic metabolites, known as the byst...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Dachs, Gabi U., Hunt, Michelle A., Syddall, Sophie, Singleton, Dean C., Patterson, Adam V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Molecular Diversity Preservation International 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255103/
https://ncbi.nlm.nih.gov/pubmed/19924084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14114517
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