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Photodynamic therapy enhances the efficacy of gene-directed enzyme prodrug therapy

INTRODUCTION: Gene-directed enzyme prodrug therapy (GDEPT) employing the cytosine deaminase (CD) gene, which encodes an enzyme that converts the nontoxic agent 5-fluorocytosine (5-FC) into the chemotherapeutic drug 5-fluorouracil (5-FU), has shown promise both in experimental animals and in clinical...

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Publicat a:Photodiagnosis Photodyn Ther
Autors principals: Christie, Catherine, Pomeroy, Aftin D, Nair, Rohit, Berg, Kristian, Hirschberg, Henry
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474194/
https://ncbi.nlm.nih.gov/pubmed/28257943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pdpdt.2017.02.016
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