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1350. Therapeutic Effects of Baloxavir Marboxil against Influenza A Virus Infection in Ferrets

BACKGROUND: Baloxavir marboxil (BXM) is a novel small molecule inhibitor of cap-dependent endonuclease that is essential for influenza virus transcription and replication. In this study, pharmacokinetic profiles of BXM and baloxavir acid (BXA), an active form of BXM, were first examined in ferrets,...

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Bibliografski detalji
Izdano u:Open Forum Infect Dis
Glavni autori: Kitano, Mitsutaka, Matsuzaki, Takanobu, Oka, Ryoko, Baba, Kaoru, Noda, Takahiro, Yoshida, Yuki, Sato, Kenji, Yoshida, Ryu, Sato, Akihiko, Kamimori, Hiroshi, Shishido, Takao, Naito, and Akira
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253920/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1181
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