1350. Therapeutic Effects of Baloxavir Marboxil against Influenza A Virus Infection in Ferrets

BACKGROUND: Baloxavir marboxil (BXM) is a novel small molecule inhibitor of cap-dependent endonuclease that is essential for influenza virus transcription and replication. In this study, pharmacokinetic profiles of BXM and baloxavir acid (BXA), an active form of BXM, were first examined in ferrets,...

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Publicado no:Open Forum Infect Dis
Main Authors: Kitano, Mitsutaka, Matsuzaki, Takanobu, Oka, Ryoko, Baba, Kaoru, Noda, Takahiro, Yoshida, Yuki, Sato, Kenji, Yoshida, Ryu, Sato, Akihiko, Kamimori, Hiroshi, Shishido, Takao, Naito, and Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253920/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1181
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