1350. Therapeutic Effects of Baloxavir Marboxil against Influenza A Virus Infection in Ferrets

BACKGROUND: Baloxavir marboxil (BXM) is a novel small molecule inhibitor of cap-dependent endonuclease that is essential for influenza virus transcription and replication. In this study, pharmacokinetic profiles of BXM and baloxavir acid (BXA), an active form of BXM, were first examined in ferrets,...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Open Forum Infect Dis
Huvudupphovsmän: Kitano, Mitsutaka, Matsuzaki, Takanobu, Oka, Ryoko, Baba, Kaoru, Noda, Takahiro, Yoshida, Yuki, Sato, Kenji, Yoshida, Ryu, Sato, Akihiko, Kamimori, Hiroshi, Shishido, Takao, Naito, and Akira
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Abstracts
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253920/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1181
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk