1350. Therapeutic Effects of Baloxavir Marboxil against Influenza A Virus Infection in Ferrets

BACKGROUND: Baloxavir marboxil (BXM) is a novel small molecule inhibitor of cap-dependent endonuclease that is essential for influenza virus transcription and replication. In this study, pharmacokinetic profiles of BXM and baloxavir acid (BXA), an active form of BXM, were first examined in ferrets,...

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Publicado en:Open Forum Infect Dis
Autores principales: Kitano, Mitsutaka, Matsuzaki, Takanobu, Oka, Ryoko, Baba, Kaoru, Noda, Takahiro, Yoshida, Yuki, Sato, Kenji, Yoshida, Ryu, Sato, Akihiko, Kamimori, Hiroshi, Shishido, Takao, Naito, and Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Abstracts
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253920/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1181
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