The antiviral effects of baloxavir marboxil against influenza A virus infection in ferrets

BACKGROUND: Baloxavir marboxil (BXM), the oral prodrug of baloxavir acid (BXA), greatly reduces virus titers as well as influenza symptoms of uncomplicated influenza in patients. OBJECTIVES: To investigate the pharmacokinetic profiles of BXA and its efficacy against influenza A virus infection in fe...

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Detalhes bibliográficos
Publicado no:Influenza Other Respir Viruses
Main Authors: Kitano, Mitsutaka, Matsuzaki, Takanobu, Oka, Ryoko, Baba, Kaoru, Noda, Takahiro, Yoshida, Yuki, Sato, Kenji, Kiyota, Kohei, Mizutare, Tohru, Yoshida, Ryu, Sato, Akihiko, Kamimori, Hiroshi, Shishido, Takao, Naito, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578299/
https://ncbi.nlm.nih.gov/pubmed/32533654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/irv.12760
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